Brazil

Crashed on takeoff from Rio de Janeiro-Santos Dumont Airport for unknown reason. The aircraft christened 'Tiete' was destroyed while the pilot Walmor Bernardoni was killed and the radio operator Oceano de Sá was injured.

During a convoy mission, the pilot was forced to attempt an emergency landing for unknown reason. The seaplane crashed in a river near Belém and some debris were found five days later, on December 3. All ten crew members were killed.

En route, the aircraft hit the slope of a mountain located near Manoel Ribeiro, some 48 km east of Rio de Janeiro. All 18 occupants were killed.

Less than one minute after take off from Rio de Janeiro-Santos Dumont Airport, while in initial climb, the three-engine aircraft hit the roof of the Naval Academy. On impact, the aircraft broke in two, one part left in the building and the second one came to rest in the Guanabara Bay. Three passengers were injured while all 18 other occupants were killed. At the time of the accident, the visibility was poor due to foggy conditions over Rio.
Crew:
Romeu Fávero, pilot 3.
Passengers:
Attilio Corrêa Lima,
Cásper Líbero,
José Gaspar d'Afonseca e Silva,
Alberto Teixiera Pequeno,
Nelson Norberto de Sousa Vieira 12.

The seaplane christened 'Bermuda Clipper' was fully loaded with passengers and crew, ready for departure from Manaus. A fire developed in the carburetor of the No. 1 engine. The pilot directed the flight mechanic to pull the fire extinguisher handle. The mechanic pulled the fuel dump handle by mistake. Flaming gas fell from the carburetor onto the gas on the water, igniting it, and causing the loss of the plane.
Source:
http://aviation-safety.net/database/record.php?id=19430727-0

Crashed in unknown circumstances in Bom Jesus da Lapa. A crew member was killed while the second one was injured.

The crew departed Atkinson Airfield in Georgetown, Guyana, at 1036LT on a ferry flight to Belém. The airplane was last seen at 1310LT by a pilot. As it failed to arrive at destination, SAR operations were initiated but eventually suspended on February 5 as no trace of the airplane nor the crew was found. It is believed that the airplane may crash around 1315LT in a jungle of the State of Amapá.
Crew:
Lt H. L. McClelland, pilot,
Pvt J. N. Gordon, air gunner,
Sgt G. R. McCollum, air gunner.

While approaching Sao Paulo from the north, the crew was informed by ATC that weather conditions at destination were poor. Few minutes later, while cruising at a too low altitude, the twin engine aircraft hit the slope of a mountain located near Pedra Branca. All 15 occupants were killed.

The crew was in charge to ferry the aircraft from NAS Norfolk to Natal. While approaching its destination, the seaplane went through a thunderstorm area and encountered a squall. Out of control, the aircraft dove into the ocean and crashed 5 miles off Natal. All 10 crew members were killed.

During the takeoff roll, one of the landing gear collapsed and punctured the wing and a fuel tank. The airplane slid for few dozen metres before coming to rest, bursting into flames. The twin engine airplane was damaged beyond repair and there were no casualties.