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The aircraft was engaged in a bombing mission over Dili. Approaching the target, the aircraft was attacked by few Japanese Mitsubishi Zero. Two crew members, among them the pilot, were killed and the aircraft was hit on the right engine and the tail as well. The crew was able to leave the combat area but was eventually forced to ditch the aircraft into the Timor Sea, some 150 miles south of Dili. The aircraft sunk and was lost while four crew members were rescued a day later by an Australian destroyer.
Crew (18th Squadron):
2nd Lt B. J. Grummels, pilot, †
C. M. Fisscher, copilot,
Cpl Van Der Weert, radio operator,
Sgt Hoek, flight engineer,
F/Sgt Ronald Stuart Horridge, wireless operator and air gunner,
Sgt Robert Gordon Tyler, wireless operator and air gunner. †

The aircraft left Shallufa at 1045LT on a maritime patrol flight over the Aegean Sea. En route, the aircraft was attacked by Flak based on a enemy merchant vessel and crashed into the sea. No trace of the aircraft nor the crew was ever found.
Crew (14th Squadron):
P/O Colin Carl Truman, pilot,
F/Sgt Jack Irvine Thompson, copilot,
F/O B. T. Connell, observer,
F/Sgt Robert Edward Herbert Hope, wireless operator and air gunner,
Sgt K. Firth, wireless operator and air gunner,
Sgt W. J. Semple, wireless operator and air gunner.

The twin engine aircraft left RAF Feltwell at 1220LT to attack the airport of Cherbourg-Maupertus with five other similar aircraft. After an uneventful mission, the aircraft was returning to its base when it crashed in unknown circumstances into The Channel, killing all four crew members.
Crew (464th Squadron):
Sgt N. E. Powell, pilot,
Sgt P. A. Nodes, navigator,
Sgt J, Dunne, wireless operator and air gunner,
Sgt S. J. Newton, air gunner.

While overflying the Atlantic Ocean by night, on the leg from Georgetown (Ascension Island) to Natal, while on a flight from Accra to Natal, the aircraft disappeared into the Ocean around 2300LT. SAR operations were conducted for several days but eventually suspended as no trace of the aircraft nor the crew was found. Two life vests were discovered on a Brazilian beach few days later.

The accident occurred when the seaplane went out of control as the pilot was trying to avoid a collision with a small boat. The aircraft sunk and was lost. Three crew members were killed while two others were rescued.

The crew left Keflavik-Meeks Field at night on an anti-submarine mission off Iceland. Some 18 minutes after take off, while flying by night and in snowy conditions, the seaplane crashed into the Atlantic Ocean, killing all eight crew members.

While cruising over the Bay of Biscay, the aircraft crashed into the sea off the Spanish coast in unknown circumstances. None of 11 occupants survived.
Crew (271st Squadron):
S/L Godfrey Allison Brown, pilot,
F/Lt Edward Thomson Halley,
P/O Peter Marsh Burton,
F/O Edwin Buckley Bowen,
F/Sgt Richard George Brett,
F/Sgt John Brister,
LAC Philip Cashmore.
Passengers:
Lt Andrew Jervis Hawkins,
Maj Harold John Palmer,
F/O William Milton Henderson,
F/O John Glen McCauley.

En route, the crew encountered poor weather conditions. In stormy weather, the seaplane went out of control and crashed into the Pacific Ocean. No trace was found.
Crew:
Lt Orrin J. McCausland, pilot,
Lt Warren K. Mesick,
Cpt James M. Kelly,
Am1 Leonard H. Davidson,
Am2 Edward R. Messenger,
Arm Arthur Dooke,
Arm Melvin F. Jurick.
Source: http://www.vpnavy.com/vp54_mishap.html

The pilot was forced to ditch the aircraft for unknown reason some 210 km off Natal. While the aircraft sunk and was lost, all eight crew members were quickly rescued.

On the leg from Georgetown to Natal, on a flight from Accra to Belém, the four engine aircraft crashed into the Atlantic ocean, some 410 km west of the Ascension Island. SAR operations were conducted but eventually suspended after few days as no trace of the aircraft nor the crew was found. The last radio contact was recorded at 0337LT.